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Dopamine
go.drugbank.com/drugs/DB00988ApprovedInvestigationalOne of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regu...
Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML)NP-6A4
go.drugbank.com/drugs/DB17599ExperimentalIt has an Orphan Drug designation from the FDA for pediatric cardiomyopathy.[A258523]
Uracil C-13
go.drugbank.com/drugs/DB16345InvestigationalUracil C-13 is under investigation in clinical trial NCT01677338 (Phase 2 Study to Evaluate the Preliminary Performance of the C13-URA Breath Test Kit in Dyspeptic Subjects).
Human Umbilical Cord Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15726Investigationalumbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over … The cells are extracted by either the explant or the enzymatic digestion method, though neither method has been characterized as the ‘standard’ thus far.
Phenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnPhenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from th...
Mixtures: COUGH - EN, COUGH - EN PLUSTisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigationalOn April 29, 2024, tisotumab vedotin was granted full FDA approval. … Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting
Ocrelizumab
go.drugbank.com/drugs/DB11988ApprovedInvestigational[A31741] In September 2024, a formulation of ocrelizumab containing [hyaluronidase (human recombinant)] was approved by the US FDA. … Developed by Genentech/Roche, ocrelizumab was approved by the FDA in March 2017 under the market name Ocrevus for intravenous injection.
Asfotase alfa
go.drugbank.com/drugs/DB09105ApprovedInvestigationalFood and Drug Administration (FDA) on October 23, 2015. Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc.
Human botulinum neurotoxin A/B immune globulin
go.drugbank.com/drugs/DB14115Approved[L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism.