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Displaying results 2521 - 2530 of 10000 in total
  1. Drug

    ZD4407

    go.drugbank.com/drugs/DB06539
    Experimental

    The drug ZD4407, an antiasthmatic developed by AstraZeneca, functions as a 5-lipoxygenase inhibitor. … It entered Phase 1 clinical trials for chronic obstructive pulmonary disease (COPD) in the United Kingdom but was discontinued during this phase in March 2003

    Synonyms: 5-(4-((2S,4R)-4-HYDROXY-2-METHYLOXAN-4-YL)THIOPHEN-2-YL)SULFANYL-1-METHYL-3H-INDOL-2-ONE, 1,3-DIHYDRO-1-METHYL-5-((4-((2S,4R)-TETRAHYDRO-4-HYDROXY-2-METHYL-2H-PYRAN-4-YL)-2-THIENYL)THIO)-2H-INDOL-2-ONE
  2. Drug

    N-(3-Cyclopropyl(5,6,7,8,9,10-Hexahydro-2-Oxo-2h-Cycloocta[B]Pyran-3-Yl)Methyl)Phenylbenzensulfonamide

    go.drugbank.com/drugs/DB02033
    Experimental

    Synonyms: N-(3-Cyclopropyl(5,6,7,8,9,10-Hexahydro-2-Oxo-2h-Cycloocta[B]Pyran-3-Yl)Methyl)Phenylbenzensulfonamide
  3. Drug

    [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)

    go.drugbank.com/drugs/DB07426
    Experimental

    Synonyms: [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
  4. Drug

    5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE

    go.drugbank.com/drugs/DB07794
    Experimental

    Synonyms: 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE
  5. Drug

    3-chloro-5-[2-chloro-5-(1H-pyrazolo[3,4-b]pyridin-3-ylmethoxy)phenoxy]benzonitrile

    go.drugbank.com/drugs/DB08459
    Experimental

    Synonyms: 3-chloro-5-[2-chloro-5-(1H-pyrazolo[3,4-b]pyridin-3-ylmethoxy)phenoxy]benzonitrile
  6. Drug

    2'-deoxythioguanosine

    go.drugbank.com/drugs/DB18117
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-amino-9-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-6-mercaptopurine, 2'-deoxy-6-thioguanosine
  7. Drug

    Iodopropynyl butylcarbamate

    go.drugbank.com/drugs/DB15666
    Investigational

    Synonyms: 3-iodo-2-propyn-1-yl N-butylcarbamate, 3-iodoprop-2-yn-1-yl butylcarbamate
  8. Drug

    KB-141

    go.drugbank.com/drugs/DB03176
    Experimental

    An anticholesteremic agent.

    Synonyms: 3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)phenylacetic acid
  9. Drug

    Cilastatin

    go.drugbank.com/drugs/DB01597
    ApprovedInvestigational

    [L7628] A newer triple-drug product was approved in July 2019 under the trade name Recarbrio which also contains [relebactam].[L4894] … Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4.

    Mixtures: TIENAM 500 MG IV ENJEKTABL FLAKON, 1 ADET, VIAPENEM 500 MG/500 MG IV İNFÜZYON İÇİN KURU TOZ İÇEREN FLAKON, 1 ADETSynonyms: (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid, (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
  10. Drug

    Piclamilast

    go.drugbank.com/drugs/DB01791
    Experimental

    Piclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. … The structure for piclamilast was first elucidated in a 1995 European patent application and exhibits the structural functionalities of cilomilast and roflumilast.

    Categories: Phosphodiesterase 4 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide, 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-p-anisamide