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Displaying results 2531 - 2540 of 10000 in total
  1. Drug

    Repotrectinib

    go.drugbank.com/drugs/DB16826
    ApprovedInvestigational

    Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively.[L48741]

    Categories: MATE 2 Inhibitors, P-glycoprotein inhibitorsSynonyms: (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9-ONE, (7S,13R)-11-Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4(5H)-One
  2. Drug

    AZD-7648

    go.drugbank.com/drugs/DB16834
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    Pidnarulex

    go.drugbank.com/drugs/DB16846
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  4. Drug

    Olprinone

    go.drugbank.com/drugs/DB16847
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 Inhibitors
  5. Drug

    Rhodamine B

    go.drugbank.com/drugs/DB16853
    Experimental

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 3-Ring
  6. Drug

    Furfural

    go.drugbank.com/drugs/DB16856
    Experimental

    Synonyms: 2-Formylofuran, 2-Furil-metanaleCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Butylated hydroxytoluene

    go.drugbank.com/drugs/DB16863
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Rosmarinic acid

    go.drugbank.com/drugs/DB16865
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Hematoxylin

    go.drugbank.com/drugs/DB16871
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    HEPES

    go.drugbank.com/drugs/DB16872
    Investigational

    Synonyms: 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid, 4-(2-Hydroxyethyl)-1-piperazineethane sulphonic acidCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting