HEPES

DB16872InvestigationalSmall molecule

HEPES: Overview.

Chemical structure of HEPES
Formula / weight
C8H18N2O4S · 238.3 g/mol (avg)
Code names
NSC-166663

Resolves to

Compound
UNIIRWW266YE9ICAS7365-45-9ChEMBLCHEMBL1232545ChEBI46755
Clinical / RWD
RxNorm1312611
Structure
InChIKeyJKMHFZQWWAIEOD-UHFFFAOYSA-NSMILESOCCN1CCN(CCS(O)(=O)=O)CC1
Targets
P22897MRC1
Transporters
P31645SLC6A4P31641SLC6A6

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
2TransportersSubstrate / inhibitor direction, not just membership
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with HEPES, and which of those have an active Phase 3 trial?

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