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Mestranol
go.drugbank.com/drugs/DB01357ApprovedWithdrawnIt is used as the estrogen component of many combination ORAL contraceptives.
Mixtures: Norinyl 1/50 28 Tab, Norinyl 1/50 21 TabCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesPolyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedPolyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. … PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.
Synonyms: PEG 300, Macrogol 300Cretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalIt has been engineered to secrete GM-CSF, an immune stimulating hormone, which also serves as the adjuvant in cancer immunotherapy. … CG0070 can potentially destroy cancer cells by two different mechanisms: direct cell killing by the virus and immune-mediated cell killing stimulated by GM-CSF.
Angelica dahurica root
go.drugbank.com/drugs/DB14255InvestigationalAngelica dahurica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Bai ZhiAcrivastine
go.drugbank.com/drugs/DB09488ApprovedAs an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension … Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D.
Mixtures: DUACT 8 MG/60 MG KAPSÜL, 30 ADETZinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalMixtures: Johnson and Johnson First Aid All Purpose 160 CT, NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 2500 MLTalquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigationalTalquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. … [L47775] Talquetamab was fully approved by the EMA on August 22, 2023.[L48822] On August 9, 2023, talquetamab was granted FDA accelerated approval.[L47770]
Synonyms: -CHAIN, (231->224'), (234->227')-BIS(DISULFIDE), IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONALChlorquinaldol
go.drugbank.com/drugs/DB13306Approved[F4549] It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. … Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan.
Mixtures: IMPETEX %0.1 + %1 KREM, 10 G, NERISONA-C %0,1 + %1 KREM, 10 GRTivozanib
go.drugbank.com/drugs/DB11800ApprovedInvestigationalIt was approved on March 10, 2021 by the FDA. Marketed by Aveo Oncology, tivozanib is a promising therapy for individuals with RCC who have not been treated successfully with other therapies.[L32524] … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAripiprazole lauroxil
go.drugbank.com/drugs/DB14185ApprovedThe patients may receive Aristada Initio in combination with a single 30 mg oral dose of aripiprazole to achieve appropriate levels of aripiprazole more rapidly. … It is a prodrug of [aripiprazole], which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors [A34289].
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists