Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs... Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment of bacterial vaginosis.
- Mechanism
- Curator reviewed · 2 references
The mechanism by which Chlorquinaldol exerts it's bacteriocidal effect is unknown. 8-hydroxyquinolines are known to be bidentate chelators of several metal ions which act as critical enzyme cofactors. However, the addition of exogenous metal ions does not appear to alter the minimum inhibitory concentration for mycobacterium tuberculosis suggesting that the primary mechanism does not rely on chelation.
- Primary indication
- Chlorquinaldol was used historically as a topical antiseptic agent for skin infections.Curator reviewed · 8 structured indications
- Formula / weight
- C10H7Cl2NO · 228.07 g/mol (avg)
- First approval
- United States, 2012
Resolves to
GPTXWRGISTZRIO-UHFFFAOYSA-NSMILESCC1=NC2=C(C=C1)C(Cl)=CC(Cl)=C2OWhat you can answer from here — as of July 07, 2026
Which drugs share a target with Chlorquinaldol, and which of those have an active Phase 3 trial?
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