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Fostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigational[L14867] It binds to and inhibits the activity of gp120, a subunit within the HIV-1 gp160 envelope glycoprotein that facilitates the attachment of HIV-1 to host cell CD4 receptors - in doing so, temsavir
Auranofin
go.drugbank.com/drugs/DB00995ApprovedInvestigationalIt has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA.
Caprylic acid
go.drugbank.com/drugs/DB04519ApprovedInvestigationalWithdrawnIt is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid-like smell that is minimally soluble in water.
FET F-18
go.drugbank.com/drugs/DB15405InvestigationalFET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).
Synonyms: 18F-FETAsparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalIt is available as intramuscular or intravenous injections. … It also facilitates the production of oxaloacetate which is needed for general cellular metabolism.
Synonyms: Asparaginase (E. coli), E. coli AsparaginaseOctenidine
go.drugbank.com/drugs/DB12624InvestigationalOctenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, LösungProducts: Octeangin antisept 2,6 mg Pastillen, Octenimed 1 mg/ml Lösung zur Anwendung in der MundhöhlePivhydrazine
go.drugbank.com/drugs/DB09252ApprovedWithdrawnIn 1960, it was widely used as an antidepressant agent but it is now discontinued.
Human interferon beta
go.drugbank.com/drugs/DB14999ApprovedInvestigationalIt is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity.[A191733,L12012]
Gimeracil
go.drugbank.com/drugs/DB09257ApprovedInvestigationalIt functions by reversibly and selectively blocking the enzyme dihydropyrimidine dehydrogenase (DPD), which is involved in the degradation of 5-FU [A31408].