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Thromboembolic disorders
go.drugbank.com/conditions/DBCOND0096925Drugs: PicotamideSynonyms: Embolism and thrombosis of unspecified sitePemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalgrowth factor receptor 2 (FGFR2) gene fusion or other rearrangements as detected by an FDA-approved test. … [A198984] Deregulated FGFR signalling pathway can lead the development of oncogenes and tumour-promoting physiological processes, such as cancer cell proliferation, enhanced angiogenesis, and evasion of
Categories: Antineoplastic and Immunomodulating AgentsCilgavimab
go.drugbank.com/drugs/DB16393ApprovedInvestigational[L39411] EVUSHELD was granted marketing authorization by the EMA on March 28, 2022,[L41454] and was approved in Canada soon after, on April 14, 2022. … [A243351, A243361, L39411] Cilgavimab is not approved for any indication by the FDA.
Categories: tixagevimab and cilgavimab, Amino Acids, Peptides, and ProteinsFlibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalIt was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder drug by Sprout Pharmaceuticals … in the brain as well as an effect on increasing norepinephrine and dopamine neurotransmitters.
Categories: Genito Urinary System and Sex HormonesInborn Errors of Bile Acid Synthesis
go.drugbank.com/conditions/DBCOND0046673Drugs: Cholic AcidSynonyms: Inborn error in primary bile acid synthesisLambert Eaton Myasthenic Syndrome (LEMS)
go.drugbank.com/conditions/DBCOND0053084Drugs: AmifampridineSynonyms: Lambert-Eaton syndrome in neoplastic diseaseFlosequinan
go.drugbank.com/drugs/DB13228ApprovedWithdrawnFlosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in drug trials.[A174979,L43942]
Categories: Vasodilators Used in Cardiac DiseasesMoexipril
go.drugbank.com/drugs/DB00691ApprovedInvestigationalIt works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. … Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension).
Mixtures: FEMPRESS PLUS 15MG/25MG, Moexipril Hydrochloride and HydrochlorothiazideCategories: ACE Inhibitors and Diuretics, moexipril and diureticsTriethylhexanoin
go.drugbank.com/drugs/DB14102InvestigationalTriethylhexanoin is an ingredient of cosmetic products as a fragrant solvent.
Categories: Compounds used in a research, industrial, or household settingProducts: 3ce Lip Color 906 Bite ItTegafur-uracil
go.drugbank.com/drugs/DB09327ApprovedIt was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd.[A32073] It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA. … Tegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4.