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Displaying results 2551 - 2560 of 3888 in total
  1. Drug

    Latrunculin B

    go.drugbank.com/drugs/DB08080
    Experimental

    Latrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge _Latrunculia magnifica_.

  2. Target

    Poly [ADP-ribose] polymerase 2

    go.drugbank.com/bio_entities/BE0003798
    TargetHumans

    Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:25043379, PubMed:27471034, PubMed:30104678, PubMed:32028527, PubMed:32939087, PubMed:34108479, PubMed...

    Synonyms: PARP-2
  3. Drug

    Bimoclomol

    go.drugbank.com/drugs/DB06258
    Experimental

    Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.

  4. Drug

    Ferrous asparto glycinate

    go.drugbank.com/drugs/DB11169
    Approved

    Ferrous asparto glycinate is an iron-amino acid chelate. It is available as a dietary supplement used in the treatment of iron deficiency and iron deficiency anemia.

    Mixtures: Se-Vate 21/7, Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate and Succinic Acid
  5. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

    go.drugbank.com/bio_entities/BE0000295
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B15
  6. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

    go.drugbank.com/bio_entities/BE0000338
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-MNLL
  7. Target

    Primary amine oxidase

    go.drugbank.com/bio_entities/BE0001222
    TargetEnzymeEscherichia coli (strain K12)

    The enzyme prefers aromatic over aliphatic amines.

    Synonyms: Copper amine oxidase
  8. Drug

    Bupivacaine

    go.drugbank.com/drugs/DB00297
    ApprovedInvestigational

    Bupivacaine is a widely used local anesthetic agent.

  9. Drug

    Firuglipel

    go.drugbank.com/drugs/DB19506
    Investigational

    Firuglipel is under investigation in clinical trial NCT02647320 (12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin).

  10. Drug

    SP1049C

    go.drugbank.com/drugs/DB04978
    Experimental

    Median survival is encouraging and correlates strongly with dose levels.[A260416]