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Tebentafusp
go.drugbank.com/drugs/DB15283ApprovedInvestigationalEven after surgical ablation or removal of the ocular tumour, almost 50% of patients with uveal melanoma develop metastatic disease. … [L39995] Tebentafusp was subsequently approved for the same indication in the EU in April 2022.[L41675]
Levacetylmethadol
go.drugbank.com/drugs/DB01227ApprovedWithdrawnLevacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased as well.[L44052,T862]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEstradiol cypionate
go.drugbank.com/drugs/DB13954ApprovedVet approvedThe primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesTilidine
go.drugbank.com/drugs/DB13787InvestigationalMixtures: TILICOMP BETA 100/8MG RET, TILICOMP BETA 100/8MG RETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesOx bile extract
go.drugbank.com/drugs/DB14016ApprovedSynonyms: Bos bovis bile, Bos taurus bileMixtures: İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 120 ADET, İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 60 ADETMedrogestone
go.drugbank.com/drugs/DB09124ApprovedWithdrawn[L1118] It was never approved by the FDA. … It was conceived as an alternative for an orally effective contraceptive option.[A31526] It was developed by Ayerst, approved in Canada in 1969 and its current status is cancelled post-marketing.
Mixtures: PRESOMEN 28 COMP 0.3/5MG, PRESOMEN 28 COMP 0.3/5MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSodium cation
go.drugbank.com/drugs/DB14516InvestigationalMixtures: VAMIN 14 IV AMINOASIT SOLÜSYONU, 500 ML, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML (PVC TORBA) SETLIVilastobart
go.drugbank.com/drugs/DB19327InvestigationalVilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).
Synonyms: G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-, gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14,Sulfadoxine
go.drugbank.com/drugs/DB01299ApprovedInvestigationalWithdrawnA long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETAS