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Metreleptin

Metreleptin is produced in _E. coli_ and differs from native human leptin by the addition of a methionine residue at its amino terminus.

Cediranib

It is being developed clinically as a once-daily oral therapy for the treatment of cancer. … The novel indole-ether quinazoline Cediranib is a highly potent (IC₅₀ < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro.

Secretin human

Although it is a gastrointestinal hormone, secretin is also considered as a neuropeptide hormone since it is also expressed in the central nervous system [A32275]. … It contains an amino acid sequence identical to the naturally occurring hormone consisting of 27 amino acids [FDA Label] that supports α-helical formation [A32275].

Lovotibeglogene autotemcel

[L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients

Quaternium-24

Piboserod

Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.

Haloprogin

The mechanism of action is unknown, but it is thought to be via inhibition of oxygen uptake and disruption of yeast membrane structure and function.

Colletotrichum coccodes

Colletotrichum coccodes is a fungus which can provoke allergic reactions. Colletotrichum coccodes extract is used in allergenic testing.

Nalorphine

It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.

Zolbetuximab

[L51923] It is specifically targeted against CLDN18.2, a membrane protein normally found in gastric mucosal cells which is overexpressed in 30-50% of gastric and gastroesophageal junction (GEJ) adenocarcinomas