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Antilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalInduction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions. … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen.
Categories: Immunoglobulin G, Increased T Lymphocyte DestructionSynonyms: e-ATG, h-ATGFelbamate
go.drugbank.com/drugs/DB00949ApprovedAlternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak inhibitory effect on GABA receptor binding sites. … Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester, 2-phenyl-1,3-propanediol dicarbamateHyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigationalHyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. … [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.
Mixtures: UR N-C Urinary Antiseptic, Me NaPhos MB Hyo 1Synonyms: [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (S)-atropineNepafenac
go.drugbank.com/drugs/DB06802ApprovedInvestigationalNepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Categories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Synonyms: 2-amino-3-benzoylbenzeneacetamideMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigational[A185888,A185891,A185897] Compared with [morphine], the gold standard reference opioid, methadone also acts as an agonist of κ- and σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA … Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersSynonyms: 6-Dimethylamino-4,4-diphenyl-3-heptanoneBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.
Mixtures: DİPROMED 5 MG + 2 MG/ML ENJEKSİYONLUK SÜSPANSİYON, DİPROMED 5 MG + 2 MG/ML ENJEKSİYONLUK SÜSPANSİYONCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalSennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label]. It is a weaker laxative than bisacodyl or castor oil[A177092].
Salts: Sennosides A and BMixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Sennosides 8.6 Mg and Docusate Sodium 50 Mg TabletsNitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Categories: Compounds used in a research, industrial, or household setting, Arteriolar Smooth Muscle, Agents Acting OnProducts: NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE, Nitroprussid-Natrium AFTPharm 50 mg/2 ml InfusionslösungHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalLong-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. … During the process, viruses are deactivated, and in the final steps, solvents used in the preparation are removed. The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus.
Categories: hepatitis B immunoglobulinSynonyms: Hepatitis B immune globulin, Hepatitis B immune globulin humanTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide