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Displaying results 2571 - 2580 of 2743 in total
  1. Drug

    Pentamycin

    go.drugbank.com/drugs/DB13571
    Experimental

    Categories: Genito Urinary System and Sex Hormones
  2. Drug

    Demegestone

    go.drugbank.com/drugs/DB13857
    Experimental

    Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  3. Drug

    Perospirone

    go.drugbank.com/drugs/DB08922
    Investigational

    It is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502].

    Synonyms: SM-9018
  4. Drug

    Faricimab

    go.drugbank.com/drugs/DB15303
    ApprovedInvestigational

    However, another set of factors, the Tie/Ang axis, comprising the transmembrane Tie-2 receptor and its soluble ligands Ang-1 and Ang-2, has been shown to play critical roles in mediating VEGF-A-induced

  5. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    See toxicity section below for a complete listing of side effects.

  6. Drug

    FT516

    go.drugbank.com/drugs/DB15732
    Investigational

    FT516 is an investigational and engineered off-the-shelf natural killer (NK) cell therapy originating from induced pluripotent stem cells (iPSC).

  7. Drug

    AVR-RD-02

    go.drugbank.com/drugs/DB17650
    Investigational

    It consists of autologous CD34+ enriched hematopoietic stem cells (HSCs) that have been genetically modified _ex vivo_ with a lentiviral vector (LV) to contain a ribonucleic acid (RNA) transcript that,

  8. Drug

    Allylestrenol

    go.drugbank.com/drugs/DB01431
    Investigational

    A synthetic steroid with progestational activity. It is widely marketed throughout Europe, including Russia and many other European countries, and is also available in Japan, Hong Kong, India, Bangladesh, Indonesia, and much of Southeast...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  9. Target

    Protein S100-A9

    go.drugbank.com/bio_entities/BE0008993
    TargetHumans

    Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme … Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3 (PubMed:19935772)

    Synonyms: Leukocyte L1 complex heavy chain
  10. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    However, it presents a significant set of anxiolytic properties with a very little sedative, amnestic or anticonvulsant effect.