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Displaying results 2571 - 2580 of 7059 in total
  1. Drug

    Etravirine

    go.drugbank.com/drugs/DB06414
    ApprovedInvestigational

    Etravirine does not inhibit human DNA polymerase alpha, beta or gamma. … Patients are advised to immediately contact their healthcare provider if a rash develops.

  2. Drug

    Nelarabine

    go.drugbank.com/drugs/DB01280
    ApprovedInvestigational

    [A2331] Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in the inhibition of DNA synthesis and cytotoxicity. … [A2332] Due to the rarity of these T-cell malignancies, nelarabine was first granted orphan drug status and a fast-track designation by the FDA to address the unmet therapeutic needs of these cancers.

    Synonyms: 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine
  3. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    Marketed as the brand name product Humulin R or Novolin R, human insulin begins to exert its effects within 30 minutes of subcutaneous administration, while peak levels occur 3-4 hours after administration … Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin.

    Products: INSUMAN COMB50 100IE/ML PA, MIXTARD 30 PENFILL100IE PA
  4. Drug

    Pegloticase

    go.drugbank.com/drugs/DB09208
    ApprovedInvestigational

    Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. … [L42425] Pegloticase has a longer terminal elimination half-life thanks to the addition of a polyethylene glycol (PEG) group.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Imnopitant

    go.drugbank.com/drugs/DB21456
    Experimental

    Imnopitant has a monoisotopic molecular weight of 550.22 Da. … Imnopitant is a small molecule drug. The usage of the INN stem '-pitant' in the name indicates that Imnopitant is a neurokinin NK1​ (substance P) receptor antagonist.

  6. Drug

    Libvatrep

    go.drugbank.com/drugs/DB21488
    Experimental

    Libvatrep has a monoisotopic molecular weight of 305.12 Da. … Libvatrep is a small molecule drug. The usage of the INN stem '-vatrep' in the name indicates that Libvatrep is a transient receptor potential vanilloid (TRPV) antagonist.

  7. Drug

    Pramiverine

    go.drugbank.com/drugs/DB19588
    Experimental

    Pramiverine has a monoisotopic molecular weight of 293.21 Da. … Pramiverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Pramiverine is a spasmolytic with a papaverine-like action.

  8. Drug

    Mofegiline

    go.drugbank.com/drugs/DB19621
    Experimental

    Mofegiline has a monoisotopic molecular weight of 197.1 Da. … Mofegiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Mofegiline is a monoamine oxydase (MAO)-inhibitor type B.

  9. Drug

    Elpetrigine

    go.drugbank.com/drugs/DB19653
    Experimental

    Elpetrigine has a monoisotopic molecular weight of 287.97 Da. … Elpetrigine is a small molecule drug. The usage of the INN stem '-trigine' in the name indicates that Elpetrigine is a sodium channel blocker, signal transduction modulator.

  10. Drug

    Palatrigine

    go.drugbank.com/drugs/DB20622
    Experimental

    Palatrigine has a monoisotopic molecular weight of 297.05 Da. … Palatrigine is a small molecule drug. The usage of the INN stem '-trigine' in the name indicates that Palatrigine is a sodium channel blocker, signal transduction modulator.