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Volanesorsen
go.drugbank.com/drugs/DB15067Approved[L16621] Volanesorsen was granted a conditional approval by the European Medicines Agency.[L16621] … Volanesorsen is an antisense oligonucleotide that binds to apoC-III mRNA to prevent its translation.
Benzonatate
go.drugbank.com/drugs/DB00868Approved[A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. … Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age.
Synonyms: 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-butylaminobenzoate, p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol esterProducts: D-TATOTranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalA propylamine formed from the cyclization of the side chain of amphetamine. … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring.
Synonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesEdrophonium
go.drugbank.com/drugs/DB01010ApprovedA rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Synonyms: 3-hydroxy-N,N-dimethyl-N-ethylanilinium, N-ethyl-3-hydroxy-N,N-dimethylaniliniumCategories: Compounds used in a research, industrial, or household settingPolyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPEG "400" indicates that the average molecular weight of the specific PEG is 400 [L1788]. … It is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Synonyms: PEG-8, Polyethylene glycol 8Mixtures: Eye Drops SY, SK Dry Eye ReliefTazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalIt is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms.
Mixtures: PIPERACILLINA E TAZOBACTAM KABI, PIPERACILLINA E TAZOBACTAM KABICategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalArsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: อะซาดิน 1 มก. / มล., TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADETBevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigationalThere is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells. … [A286054] This off-label practice was formalized with the approval of Lytenava (bevacizumab-vikg in the US; bevacizumab gamma in the EU/UK), the first ophthalmic formulation of bevacizumab developed specifically
Synonyms: 贝伐珠单抗International brands: 安倍斯, 安维汀Chloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approvedChloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. … [A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and [mefloquine].
Synonyms: N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamineInternational brands: Nivaquine BIndalpine
go.drugbank.com/drugs/DB08953ApprovedWithdrawnHowever, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market. … Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 Substrates