Search
Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigationalDabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor [dabigatran]. … [A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated.
Cosibelimab
go.drugbank.com/drugs/DB15770ApprovedInvestigationalOn December 13, 2024, cosibelimab was approved by the FDA for the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma [L52690] as the first approved anti-PD-L1 therapy in the … Cosibelimab is a human IgG1 lambda monoclonal antibody directed against programmed death ligand-1 (PD-L1).
Haloprogin
go.drugbank.com/drugs/DB00793ApprovedWithdrawnHaloprogin is used as a topical ointment or cream in the treatment of Tinea infections. … Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton).
Somatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawnIt is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating … [DB00104] is a long-acting analogue of somatostatin that inhibits the release of a number of hormones, and is clinically used to relieve symptoms of uncommon gastroenteropancreatic endocrine tumours, as
Crovalimab
go.drugbank.com/drugs/DB16128ApprovedInvestigationalCrovalimab is a humanized monoclonal antibody and complement C5 inhibitor.[L50908] It consists of two heavy chains (451 amino acid residues each) and two light chains (217 amino acid residues each). … [A263958] It soon gained its approval in Japan in the next month,[A263958] and in the USA in June of the same year.
Albutrepenonacog alfa
go.drugbank.com/drugs/DB13884ApprovedIt is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] … Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin).
Products: IDELVION 250 IU powder and solvent for solution for injection, IDELVION 500 IU powder and solvent for solution for injectionAcetyldigitoxin
go.drugbank.com/drugs/DB00511ApprovedCardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Desglucolanatoside ARidogrel
go.drugbank.com/drugs/DB01207ExperimentalRidogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction. … However, there currently are no clinical indications for preferential use of ridogrel over aspirin.
Categories: Thromboxane-A Synthase, antagonists & inhibitorsGlymidine
go.drugbank.com/drugs/DB01382ApprovedThe mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral … Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin.
Categories: combinations of sulfonamidesBezlotoxumab
go.drugbank.com/drugs/DB13140Approved[L46976] On November 22, 2016, the Committee for Medicinal Products for Human Use of the European Medicines Agency recommended the granting of a marketing authorization. … Bezlotoxumab is a fully humanized ImmunoglobulinG1 (IgG1) kappa monoclonal antibody that binds to _Clostridium difficile_ toxin B and neutralizes its effects.