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Carbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigationalCarbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, ...
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: CARBAMAZEPIN 200 1A PHEnapotamab vedotin
go.drugbank.com/drugs/DB16156InvestigationalEnapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).
Synonyms: Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide with human humax-axl .kappa.-chain, dimer tetrakis(thioether) with vedotinFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigationalFormoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racem...
Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIbuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in ...
Synonyms: (±)-p-isobutylhydratropic acid, (±)-2-(p-isobutylphenyl)propionic acidMixtures: Advil PM, Advil PMCalcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Zilovertamab
go.drugbank.com/drugs/DB18403InvestigationalSynonyms: Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa.-chain, dimerAOC 1001
go.drugbank.com/drugs/DB18620InvestigationalDelpacibart (AOC 1001) is being investigated in a global study for the treatment of Myotonic Dystrophy type 1 (DM1) in clinical trial NCT06411288
Synonyms: Immunoglobulin G1 [233-alanine,234-alanine,327-arginine,de-446-lysine], anti-(human type 1 transferrin receptor) (human-Mus musculus clone AV05 γ1-chain), disulfide with human-Mus musculus clone AV05 κ-chainRelatlimab
go.drugbank.com/drugs/DB14851ApprovedInvestigational[L41305] As immune checkpoint inhibitors have limited efficacy when used alone, drugs like relatlimab have been trialed in combination with other checkpoint inhibitors - for example, PD-1 inhibitors like … [A246155] Relatlimab received FDA approval in March 2022, alongside the PD-1 inhibitor [nivolumab] in the combination product Opdualag (Bristol-Myers Squibb), for the treatment of unresectable or metastatic
Allantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalAllantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, th...
Products: Dr Young 2p Blemish Base SPF35 PA, Young 2P Pearl Brightening Balm SPF35 PAToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalOne mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the inhibition … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, Programmed Death Receptor-1 Blocking Antibody