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Displaying results 251 - 260 of 10000 in total
  1. Drug

    Latanoprostene bunod

    go.drugbank.com/drugs/DB11660
    Approved

    Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure. … As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod opthalmic solution), 0.024% for the indication of reducing intraocular pressure in patients with open-angle glaucoma

  2. Drug

    Recombinant human alkaline phosphatase

    go.drugbank.com/drugs/DB17672
    Investigational

    Synonyms: recAP
  3. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

    Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDProducts: T & B, TQ OFTAMOX® UD
  4. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

    Products: VP-TEC, EPOSIN CONCENTRADO PARA SOLUCION DE INFUSION DE 20 MG/ML
  5. Pathway

    Histamine H1 Receptor Activation

    smpdb.ca/view/SMP0063452
    Signaling

    This results in the dissociation of a Gαq-GTP monomer and a Gβγ dimer from the receptor . … Upon binding by histamine, the H1 receptor allosterically activates the G-protein by exchanging GDP for GTP at the G-protein's alpha subunit (Gαq).

    Drugs: Calcium
    Enzymes: Histamine H1 receptor, Inositol 1,4,5-trisphosphate receptor type 1
  6. Drug

    Boserolimab

    go.drugbank.com/drugs/DB17452
    Investigational

    Synonyms: Immunoglobulin G1-kappa, anti-(homo sapiens CD27 (TNFRSF7, tumor necrosis factor receptor (TNFR) superfamily member 7))
  7. Drug

    Vonlerolizumab

    go.drugbank.com/drugs/DB16352
    Investigational

    Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Ar...

    Synonyms: Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody: .gamma.1 heavy chain (1-447), Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody
  8. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    [A190273] The most popular of the third generation dihydropyridines is [amlodipine].[A190273] Nifedipine was granted FDA approval on 31 December 1981.[L11383] … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].

    Mixtures: NIF TEN 50, NIF-TEN CAPSULEProducts: NIFEDIPIN AL T 20 RETARD, NIFEDIPIN RATIO20MG/ML TR
  9. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as … Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094].

    Mixtures: FITODERM TCProducts: TM-Clotrimazole, Kerasal foot and toe
  10. Drug

    Anti-CD7 CAR T-cell therapy

    go.drugbank.com/drugs/DB18128
    Experimental

    Synonyms: A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7, Anti-CD7 CAR T-cell therapy