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Zaleplon
go.drugbank.com/drugs/DB00962ApprovedIllicitZaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. … Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Categories: GABA-A Receptor Agonists, gamma-Aminobutyric Acid A Receptor AgonistSynonyms: 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilideCyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigational[A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond. … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977.
Mixtures: DOBRIX ®, Therabenzaprine-90-5Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalZolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … Research also shows that zolpidem is rapid and effective in restoring brain function for patients in a vegetative state following brain injury.
Mixtures: Gabazolpidem-5, Sentrazolpidem PM-5Categories: GABA-A Receptor Agonists, gamma-Aminobutyric Acid A Receptor Positive ModulatorAtidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigationala lentiviral vector encoding the human arylsulfatase A (ARSA) gene. … [L45196] It was granted FDA approval under the brand name Lenmeldy in March 2024.[L50256]
Synonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene, Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid sequenceNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
go.drugbank.com/drugs/DB14427ApprovedInvestigationalNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Mixtures: MENVEO®, MENVEO®Synonyms: Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigenPepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnInterestingly, recent research has suggested that pepsin participates in the digestion of nucleic acids [L2391]. … Pepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing practice [L2363].
Mixtures: Debiline H, Glutamic Acid HCl Betaine HCl W PepsinCategories: Pepsin A, antagonists & inhibitorsCollagenase clostridium histolyticum
go.drugbank.com/drugs/DB00048ApprovedInvestigational[L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum.
Synonyms: Clostridiopeptidase AOctanoyl-Coenzyme A
go.drugbank.com/drugs/DB02910ExperimentalCategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-RingSynonyms: Octanoyl-Coenzyme A