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Displaying results 251 - 260 of 1186 in total
  1. Drug

    Calcium carbonate

    go.drugbank.com/drugs/DB06724
    ApprovedInvestigational

    Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ...

    Mixtures: Meds on the GoProducts: Medi First Antacid, Medi First Plus Antacid
  2. Drug

    AD-114

    go.drugbank.com/drugs/DB18285
    Experimental

    Synonyms: Human single domain antibody-like protein inhibitor of the chemokine receptor type 4
  3. Drug

    Capmatinib

    go.drugbank.com/drugs/DB11791
    ApprovedInvestigational

    Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades … [A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC.

  4. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer
  5. Drug

    RAD 502

    go.drugbank.com/drugs/DB17328
    Experimental

    Synonyms: Lutetium-177 labeled humanized monoclonal antibody targeting leucine rich repeat containing 15 (LRRC15)
  6. Drug

    Domperidone

    go.drugbank.com/drugs/DB01184
    ApprovedInvestigationalVet approved

    A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

    Categories: Dopamine D2 Receptor AntagonistsProducts: MOD
  7. Drug

    Acetaminophen

    go.drugbank.com/drugs/DB00316
    ApprovedInvestigational

    Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antip...

    Mixtures: Meds on the Go, Meds on the GoProducts: PARACETAMOL 500 FAIR-MED, PARACETAMOL 500 MG IPA MED
  8. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Categories: Angiotensin 2 Receptor Blocker, Angiotensin II receptor antagonistsProducts: RECEP-H
  9. Drug

    Telisotuzumab vedotin

    go.drugbank.com/drugs/DB15104
    ApprovedInvestigational

    [L53158] The c-Met protein is found to be overexpressed in approximately 25% of advanced EGFR wild type, non-squamous NSCLC patients and is associated with poor prognosis and limited treatment options. … Telisotuzumab vedotin is an antibody-drug conjugate comprising [telisotuzumab], a c-Met-directed humanized IgG1κ monoclonal antibody, conjugated to monomethyl auristatin E (MMAE), a small molecule microtubule-disrupting

  10. Drug

    Recifercept

    go.drugbank.com/drugs/DB17899
    Investigational

    Synonyms: Recombinant human fibroblast growth factor receptor 3, Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46)