Search
Linezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Products: DILOZELD-UF 2MG/ML SOLUCIÓN PARA INFUSIÓNAfamelanotide
go.drugbank.com/drugs/DB04931Approved[L9086] It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer … [L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]
Categories: Protectives Against UV-Radiation, Protectives Against UV-Radiation for Systemic UseFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigational[L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012. … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.
Products: NEUPOGEN 30 MIO U 0.3MG/ML VIAL, INMUNEF 30 UI SOLUCION INYECTABLEInsulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L50758,A263818] Insulin icodec was approved by Health Canada in March 2024 for the treatment of adult patients with type 1 or 2 diabetes mellitus,[L50758] and was subsequently approved by the EMA in … [L51078] In July 2024, the US FDA rejected the approval of insulin icodec, citing concerns regarding hypoglycemia and the indication being sought for type 1 diabetes mellitus.
Benzethonium
go.drugbank.com/drugs/DB11125ApprovedThere is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … Benzethonium was identified as a novel cancer-specific compound by cell-based small-molecule screen [A32298].
Mixtures: Tough Guy Hand Sanitizer Wipes Tough GuyProducts: Bob Barker Antibacterial un-wrapped bodyCefixime
go.drugbank.com/drugs/DB00671ApprovedInvestigational[L49293] The beta-lactam ring of cefixime inhibits bacterial cell wall synthesis by binding to the penicillin-binding proteins which will then result in lysis.
Products: Cefixime 400 mg UD, CEFIXIMA MK 20MG/MLSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalNevertheless, it is because of this mechanism that sildenafil is also indicated for treating pulmonary arterial hypertension but is also additionally notorious for interacting with various anti-anginal … In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850
Products: VIATHER BY CORNEElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigational[L39160, L39277] A similar booster dose is also available in the US for patients 18 years of age and older. … In clinical trials, there were no differences in the safety profiles between younger and older (65 years of age and older) study participants.
Rivanicline
go.drugbank.com/drugs/DB05855ExperimentalIt was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8.
Synonyms: (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amineAvobenzone
go.drugbank.com/drugs/DB09495ApprovedInvestigationalAvobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as ...
Mixtures: Banana Boat Ultra Defence SPF 30 for UK, Sun Bum 50