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Levamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117, A178123] Levamisole was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. … [A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.
Products: OBAT CACING NO.17 KAM CEK SAN, PARAKS 40 MG/5 ML ŞURUP, 30 MLPropafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalAn antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: Nu-propafenone, PROPAFENON AL 150Formoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigational[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration … of action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication.
Mixtures: FLUTIFORM 125/5UG 3X120 HU, BUDEMAR DUO® FORMOTEROL FUMARATO 6 MCG + BUDESONIDA 100 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: LINEZOLID AL 600 MG FTA, ZIZOLID 100 MG / 5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 150 MLDipyridamole
go.drugbank.com/drugs/DB00975ApprovedInvestigationalA phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.
Mixtures: Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg, Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mgInternational brands: Cleridium 150Pramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalliving due to symptoms that progress over time [A176858]. … It is a _non-ergot dopamine agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) [A176867].
Products: Nu-pramipexole, MIRAPEX ® ER 1.5 MG TABLETAS DE LIBERACIÓN PROLONGADAIopromide
go.drugbank.com/drugs/DB09156ApprovedIt functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration.
Categories: Compounds used in a research, industrial, or household settingProducts: RAVİSTU 300 MG I/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, İOPOLİMİD 370 MG I/ML ENJEKSİYONLUK ÇÖZELTİ, 100 MLChloramphenicol
go.drugbank.com/drugs/DB00446ApprovedInvestigationalVet approvedWithdrawnAn antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically. … (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this
Mixtures: CORTIFENOL H POMADA OFTALMICA 4 G, ยาฉีดมาโนซีติน 250 มก.Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C19 InhibitorsGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. … [L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]
Mixtures: DUO-ANGLUCID, DUPLAX 250 MG/1.25 MG FILM KAPLI TABLET, 120 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalEverolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. … It is currently used as an immunosuppressant to prevent rejection of organ transplants.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: EVEROLIMUS DR. REDDY'S, VOTUBİA 10 MG TABLET, 100 ADET