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Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalWhen used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies as ribavirin monotherapy is not efficacious in the treatment of chronic hepatitis C infection … The potential use of ribavirin as a treatment for acute myeloid leukemia is currently under investigation.
Safflower oil
go.drugbank.com/drugs/DB09446ApprovedInvestigationalWithdrawnSafflower oil is approved for use as an indirect additive in food contact substances and is readily available as a food ingredient. … Safflower oil with a higher content of polyunsaturated fatty acids is more commonly used as an edible oil.
rsPSMA Vaccine
go.drugbank.com/drugs/DB06361ApprovedWithdrawnrsPSMA Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et al., PNAS 100:12590, 2003). … Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases.
Valbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigationalThe reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … [A261165] However, challenges in using [tetrabenazine] as a treatment of tardive dyskinesia included frequent dosing and safety and tolerability concerns.
Synthetic Conjugated Estrogens, A
go.drugbank.com/drugs/DB09317ApprovedConjugated Equine Estrogens (CEEs) are derived from the urine of pregnant mares and contain a blend of at least 10 estrogen derivatives. … There is currently no generic form of CEEs available as a detailed analytical characterization of the active ingredients or of their estrogenic activity is not available at this time.
Synonyms: Estrogens, Conjugated Synthetic A, Synthetic Conjugated Estrogens, AAcetophenazine
go.drugbank.com/drugs/DB01063ApprovedAcetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. … It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
Cefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigationalCefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. … Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.
Ibudilast
go.drugbank.com/drugs/DB05266InvestigationalIbudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume … (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan.