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Cabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalCabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … [A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: CABATAX 60 MG/1,5 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET, NEUTAXAN 60 MG/ 1.5 ML İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADETCalcium carbimide
go.drugbank.com/drugs/DB09116ApprovedWithdrawnCalcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. … Calcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side effect profile either when it is consumed accompanied by alcohol or without it.
Oxantel
go.drugbank.com/drugs/DB13670InvestigationalOxantel is an anthelmintic drug that targets parasitic acetylcholine receptors.[A275093, A275098]
Mixtures: PAMOATO DE PIRANTEL/PAMOATO DE OXANTEL SUSPENSION, PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN.Ethchlorvynol
go.drugbank.com/drugs/DB00189ApprovedIllicitWithdrawnEthchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Cobicistat
go.drugbank.com/drugs/DB09065ApprovedInvestigationalAlthough it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.
Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET, GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADETCategories: Metabolic Side Effects of Drugs and Substances, Antivirals used in combination for the treatment of HIV infectionsWheat bran
go.drugbank.com/drugs/DB10685ApprovedWheat bran allergenic extract is used in allergenic testing.
Categories: Diet, Food, and NutritionNOP-1A
go.drugbank.com/drugs/DB15208InvestigationalNOP-1A is under investigation in clinical trial NCT01198197 (PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A).
Silver
go.drugbank.com/drugs/DB12965ApprovedInvestigationalSilver and its compounds have been used in trials studying the management of dental caries since the 1800s, and they may be found in dental pastes as an active ingredients. … Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity.
Products: Yan Plus Super MedicPalovarotene
go.drugbank.com/drugs/DB05467ApprovedFibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million individuals, is an exceptionally rare genetic disorder. … ], which are derivatives of [vitamin A].
Piperacetazine
go.drugbank.com/drugs/DB06808ApprovedVet approvedWithdrawnPiperacetazine was an antipsychotic.