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Displaying results 2601 - 2610 of 8974 in total
  1. Drug

    Danaparoid

    go.drugbank.com/drugs/DB06754
    ApprovedWithdrawn

    Danaparoid sodium is the common salt form in therapeutic preparations and is typically administered subcutaneously. … While it was initially approved by the FDA as Orgaran™, danaparoid was withdrawn by Organon International on August 14, 2002, due to a shortage in drug substance by the manufacturer.

  2. Drug

    Fidaxomicin

    go.drugbank.com/drugs/DB08874
    ApprovedInvestigational

    [A190486] The approved indication of fidaxomicin was expanded by the FDA in January 2020 to include pediatric patients over the age of 6 months in the treatment population.[L11575] … [A190486] The minimum inhibitory concentration (MIC<sub>90</sub>) for fidaxomicin is four times less than that of [vancomycin], which was the primary drug of choice for _C. difficile_ infection before

  3. Drug

    Avacopan

    go.drugbank.com/drugs/DB15011
    ApprovedInvestigational

    two main forms of ANCA-associated vasculitis - in combination with [rituximab] or [cyclophosphamide]. … by the presence of ANCAs in the serum.

  4. Drug

    Glycerol phenylbutyrate

    go.drugbank.com/drugs/DB08909
    ApprovedInvestigational

    Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.

  5. Drug

    Belladonna

    go.drugbank.com/drugs/DB13913
    Approved

    The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb eye-drops by women to dilate the pupils of the eyes for aesthetic purposes. … [DB00572] is a non-selective muscarinic antagonist that is mainly used as an adjunct for anaesthesia.

    Mixtures: BIOGASTRIN TOZ, 60 G
  6. Drug

    Drospirenone

    go.drugbank.com/drugs/DB01395
    ApprovedInvestigational

    [L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and premenstrual dysphoric disorder (PMDD). … Drospirenone has been the subject of widespread safety concern due to the possibility of an increased risk of venous thromboembolism associated with its use.

    Mixtures: Lo-ZumandimineCategories: Hormonal Contraceptives for Systemic Use
  7. Drug

    Deucravacitinib

    go.drugbank.com/drugs/DB16650
    ApprovedInvestigational

    [A246943] Deucravacitinib was first approved by the FDA in September 2022 to treat moderate-to-severe plaque psoriasis. … to this therapeutic target.

  8. Drug

    Helium

    go.drugbank.com/drugs/DB09155
    ApprovedInvestigationalVet approved

    Helium has lower density than air and generates less resistance than to provide improved lung ventilation. … It is also used as an analytical reagent in diagnostic/imaging tests to detect respiratory function of the patient.

    Mixtures: Co-HE-O2-N2 Mixture
  9. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836]. … Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837].

    Categories: Antihypertensive Agents Indicated for Hypertension
  10. Drug

    Acalabrutinib

    go.drugbank.com/drugs/DB11703
    ApprovedInvestigational

    It also received Orphan Drug designation, which provides incentives to assist and encourage the development of drugs for rare diseases. … expected to demonstrate fewer adverse effects owing to minimized bystander effects on targets other than BTK.