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Displaying results 2611 - 2620 of 10000 in total
  1. Drug

    Denotivir

    go.drugbank.com/drugs/DB21323
    Experimental

    Denotivir is a small molecule drug. The usage of the INN stem '-vir' in the name indicates that Denotivir is a antiviral. Denotivir has a monoisotopic molecular weight of 371.05 Da.

  2. Drug

    Osaterone

    go.drugbank.com/drugs/DB21382
    Experimental

    Osaterone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Osaterone is a antiandrogen. Osaterone has a monoisotopic molecular weight of 364.14 Da.

  3. Drug

    Sinitrodil

    go.drugbank.com/drugs/DB21396
    Experimental

    Sinitrodil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Sinitrodil is a vasodilator. Sinitrodil has a monoisotopic molecular weight of 238.06 Da.

  4. Drug

    Tipiracil

    go.drugbank.com/drugs/DB09343
    ApprovedInvestigational

    Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. … The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism.

  5. Target

    Nuclear factor of activated T-cells, cytoplasmic 1

    go.drugbank.com/bio_entities/BE0004878
    TargetHumans

    Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation a...

    Synonyms: NFAT transcription complex cytosolic component
  6. Drug

    Flutrimazole

    go.drugbank.com/drugs/DB13425
    Investigational

    Flutrimazole is a topical imidazole antifungal agent with broad spectrum activity.[A275033]

    Categories: Genito Urinary System and Sex Hormones, Antifungals for Topical Use
  7. Drug

    Palucorcel

    go.drugbank.com/drugs/DB17955
    Investigational

    Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. … Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.

  8. Drug

    Pinaverium

    go.drugbank.com/drugs/DB09090
    ApprovedInvestigational

    Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets. … Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function.

  9. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and … apoptosis of cancer cells, is thought to be the main mechanism of action of bortezomib.

    Synonyms: [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid, [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic AcidProducts: 26-s
  10. Drug

    Ifosfamide

    go.drugbank.com/drugs/DB01181
    ApprovedInvestigational

    Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.