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Nabiximols
go.drugbank.com/drugs/DB14011InvestigationalIn Canada, Sativex® has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have not responded … Sativex® has also received a Notice of Compliance with Conditions (NOC/c) for use as an adjunctive treatment for the symptomatic relief of neuropathic pain in adult patients with multiple sclerosis (MS
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsClioquinol
go.drugbank.com/drugs/DB04815ApprovedVet approvedWithdrawnClioquinol was withdrawn in 1983 due to neurotoxicity.
Synonyms: 7-Iodo-5-chloroxine, 5-Chloro-7-iodo-8-quinolinolMixtures: LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 GSotagliflozin
go.drugbank.com/drugs/DB12713ApprovedInvestigational[L39705] Its potency in inhibiting SGLT2 is similar to that of other SGLT2 inhibitors, such as [canagliflozin] and [dapagliflozin], but its potency in inhibiting SGLT1 is >10-fold higher than its predecessors … /m<sup>2</sup>.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersMorus alba root bark
go.drugbank.com/drugs/DB14271InvestigationalMorus alba root bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Sang Bai PiCinaciguat
go.drugbank.com/drugs/DB16126InvestigationalCinaciguat is under investigation in clinical trial NCT01067859 (A Phase Iib Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 ΜG/h, 10 ΜG/h) Given Intravenously to Patients
Teclistamab
go.drugbank.com/drugs/DB16655ApprovedInvestigational[L43612] Teclistamab was later granted accelerated approval by the FDA on October 25, 2022.[L43617] … [A253587] On August 24, 2022, the European Commission (EC) granted conditional marketing authorization of teclistamab as first-in-class bispecific antibody for the treatment of multiple myeloma, marking
Stearic acid
go.drugbank.com/drugs/DB03193ApprovedStearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Mixtures: Isa Knox Ageless Serum Makeup Base 10, O Hui Veil Fit Dual Foundation 10Synonyms: C18:0Amphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigationalAmphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. … [A18540] The first product of Smith, Kline and French was approved by the FDA on 1976.[L5194] During World War II, amphetamine was used to promote wakefulness in the soldiers.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsZoliflodacin
go.drugbank.com/drugs/DB12817ApprovedInvestigational[A274938,L54748] It is indicated as a single-dose oral therapy for the treatment of uncomplicated urogenital gonorrhea.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesEflapegrastim
go.drugbank.com/drugs/DB15001ApprovedInvestigationalFebrile neutropenia (FN), defined as the co-occurrence of fever (temperature > 38 ◦C) and severe neutropenia (ANC < 500 cells/mm<sup>3</sup>), is a potential side effect of myelosuppressive chemotherapy … [L43135] Eflapegrastim is a form of recombinant human G-CSF comprising a human G-CSF analog coupled to the Fc fragment of human IgG4 via a polyethylene glycol linker.