Clioquinol

DB04815ApprovedVet approvedWithdrawnSmall moleculeStandardized Chemical Allergen

Clioquinol is an antifungal cream used to treat a variety of fungal infections. Clioquinol was withdrawn in 1983 due to neurotoxicity.

Chemical structure of Clioquinol
Mechanism
Curator reviewed
Primary indication
Used as a topical antifungal treatment.Curator reviewed · 56 structured indications
Formula / weight
C9H5ClINO · 305.5 g/mol (avg)
First approval
Canada, 1997 · United States, 2012
Also known as
Chloroiodoquin · Iodochlorhydroxyquin · Iodochlorhydroxyquinoline · Iodochlorohydroxyquin · Iodochloroxyquinoline
Code names
Caswell No. 193
Brand names
  • Locacorten Vioform

Resolves to

Compound
UNII7BHQ856EJ5CAS130-26-7ChEMBLCHEMBL497ChEBI74460PubChem2788
Clinical / RWD
RxNorm5942ATCD08AH30ATCD09AA10ATCG01AC02PharmGKBPA449039
Structure
InChIKeyQCDFBFJGMNKBDO-UHFFFAOYSA-NSMILESOC1=C(I)C=C(Cl)C2=C1N=CC=C2
Targets
P41145OPRK1

What you can answer from here — as of May 03, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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56Structured indicationsCondition, population, route and combination as fields, not prose
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65Marketed productsAcross 8 countries and 36 labellers
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6ATC codesIncluding every combination product, plus 20 drug categories
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7+ReferencesStructured and connected to the statements they support
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