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Nisoldipine
go.drugbank.com/drugs/DB00401ApprovedNisoldipine may be used in alone or in combination with other agents in the management of hypertension.
Categories: Antihypertensive Agents Indicated for HypertensionRG2417
go.drugbank.com/drugs/DB05055InvestigationalRG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential … for cell metabolism.
Fursultiamine
go.drugbank.com/drugs/DB08966ApprovedCompound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
GTS-21
go.drugbank.com/drugs/DB05708InvestigationalIn all studies, the compound was well tolerated. … In a Phase I multi-dose, double-blind, placebo controlled study in healthy adults, GTS-21 also demonstrated cognitive enhancement across all doses, with a statistically significant improvement in attention
Umifenovir
go.drugbank.com/drugs/DB13609Investigational[A191475] It has been in use in Russia for approximately 25 years and in China since 2006. … Umifenovir is an indole-based, hydrophobic, dual-acting direct antiviral/host-targeting agent used for the treatment and prophylaxis of influenza and other respiratory infections.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigational[L8453,L8459] It was first approved for use in the United States in 2014. … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]
Leflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many othe...
Contusugene ladenovec
go.drugbank.com/drugs/DB05322InvestigationalAdvexin is a well-tolerated and efficacious treatment for numerous cancers, both as monotherapy and in combination with radiation and/or chemotherapy agents.
MBO7133
go.drugbank.com/drugs/DB04999ExperimentalHowever, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of an enzyme in the liver that is required for the conversion of araC to araCMP, the first step … MB07133 uses our HepDirect technology to target a prodrug form of araCMP specifically to the liver.
Halcinonide
go.drugbank.com/drugs/DB06786ApprovedWithdrawnHalcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment.