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Nitrazepam
go.drugbank.com/drugs/DB01595ApprovedA benzodiazepine derivative used as an anticonvulsant and hypnotic.
Products: NITRAPAM TABLETS 5MGLipegfilgrastim
go.drugbank.com/drugs/DB13200ApprovedIt is used as an alternate to [DB00019] for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. … Since July 2013, lipegfilgrastim is marketed by the EMA as Lonquex for subcutaneously injection, where it is administered once following cytotoxic chemotherapy for each chemotherapy cycle in adult patients
19-norandrostenedione
go.drugbank.com/drugs/DB01434ExperimentalIllicitAfter 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. … In the body 19-norandrostenedione is rapidly metabolized into [nandrolone], also known as nortestosterone.
Iroxanadine
go.drugbank.com/drugs/DB05444ExperimentalIt induces phosphorylation of p38 SAPK, which plays an important role in EC homeostasis. endothelial cell (EC). … BRX-235 (iroxanadine) is a a novel small molecule synthesized by Biorex, Hungary that acts as a cardioprotective agent.
Tromethamine
go.drugbank.com/drugs/DB03754ApprovedInvestigational(From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424) … It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used
Iodipamide
go.drugbank.com/drugs/DB04711ApprovedWithdrawnIodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Unoprostone
go.drugbank.com/drugs/DB06826ApprovedWithdrawnUnoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Technetium Tc-99m red blood cells
go.drugbank.com/drugs/DB09493ApprovedWithdrawnTechnetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging … It is suggested that _in vitro_ labelling improves the heart-to-background ratio during imaging [A32181].
Insulin glulisine
go.drugbank.com/drugs/DB01309ApprovedDue to its duration of action of around 5 hours, Apidra is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the … This recombinant hormone differs from native human insulin in that the amino acid asparagine at position B3 is replaced by lysine and the lysine at position B29 is replaced by glutamic acid.
Eplontersen
go.drugbank.com/drugs/DB16199ApprovedInvestigational[A262985] As eplontersen targets both the WT and mutant TTR, it poses tremendous promises as a treatment. … It was previously investigated as a potential treatment for hereditary transthyretin-mediated amyloidosis.