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Didanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalThis modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Synonyms: 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olProducts: DIDANOSINA 400 MG, DIDAN 100 MG TABLETAZopapogene imadenovec
go.drugbank.com/drugs/DB24672ApprovedInvestigationalFood and Drug Administration (FDA) for the treatment of adults with RRP, receiving full FDA approval on August 15, 2025.[L54081] … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory
Synonyms: under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, Replication-deficient gorilla adenovirus vector (strain GC46) encoding human papillomavirus (HPV) type 6 and type 11 antigens comprising 11 epitopes derived from regions of the E2, E4, E6, and E7 proteinsDarbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Products: g/0.5 ml, g/0.5 mlMethantheline
go.drugbank.com/drugs/DB00940ApprovedAntispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. … Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems
Luliconazole
go.drugbank.com/drugs/DB08933ApprovedInvestigationalLuliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes.
Belumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigationalof systemic therapy. … Belumosudil is used in the treatment of chronic graft-versus-host disease (GVHD) and has been investigated for the treatment of pulmonary arterial hypertension.
Formestane
go.drugbank.com/drugs/DB08905ApprovedWithdrawnFormestane suppresses estrogen production from anabolic steroids or prohormones. … Some clinical data has suggested that the clinically recommended dose of 250mg was too low.
Synonyms: 4-OH-AGallium nitrate
go.drugbank.com/drugs/DB05260ApprovedInvestigationalGallium nitrate is a nitrate salt of [DB14524], a heavy metal that has been used as a diagnostic agent.[A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. … [A17097] GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US for reasons other than safety or effectiveness.
Phosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalIn apoptosis, phosphatidyl serine is transferred to the outer leaflet of the plasma membrane. This is part of the process by which the cell is targeted for phagocytosis. … Because of the potentail cognitive benefits of phosphatidylserine, the substance is sold as a dietary supplement to people who believe they can benefit from an increased intake.
Carob
go.drugbank.com/drugs/DB10852ApprovedCarob allergenic extract is used in allergenic testing.
Categories: Compounds used in a research, industrial, or household setting