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L-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalLevacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] In September 2024, the FDA approved levacetylleucine for the treatment of select patients with NPC.[L51444]
Synonyms: N-acetyl leucine, N-acetylleucineLycopene
go.drugbank.com/drugs/DB11231ApprovedLycopene is a naturally occurring red carotenoid pigment that is responsible for red to pink colors seen in tomatoes, pink grapefruit, and other foods [A27242]. … However, lycopene is a potent antioxidant molecule that scavenges reactive oxygen species (ROS) singlet oxygen. Tomato lycopene extract is used as a color additive in food products.
Categories: Compounds used in a research, industrial, or household settingKappadione
go.drugbank.com/drugs/DB09332Approvednot available in North America [L1543]. … It has been found to have carcinogenic potential in mammalian cells as well as cytotoxic properties [L1544].
Crizanlizumab
go.drugbank.com/drugs/DB15271ApprovedInvestigational[L10097] Sickle cell disease is a genetically inherited condition prevalent in the Middle East, Africa, and certain parts of India. … Crizanlizumab is a humanized IgG2 monoclonal antibody used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease.
Calcium alginate
go.drugbank.com/drugs/DB13372ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingMephenesin
go.drugbank.com/drugs/DB13583ApprovedWithdrawnMephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression [A32760]. It first entered use in the 1950s.
Nisoldipine
go.drugbank.com/drugs/DB00401ApprovedNisoldipine may be used in alone or in combination with other agents in the management of hypertension. … Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
International brands: Di Yi Xin, Ji Ni Le ErBenzyl alcohol
go.drugbank.com/drugs/DB06770ApprovedInvestigationalMixtures: Fast Freeze Lidocaine Roll-OnNormethadone
go.drugbank.com/drugs/DB11609ApprovedIllicitNormethadone is used as an opioid antitussive in combination with [DB11610]. It is marketed in Canada by Valeant under the tradename Cophylac.
Synonyms: Isomethadone IMethylparaben
go.drugbank.com/drugs/DB14212ApprovedMethylparaben is used in allergenic testing.
Categories: Compounds used in a research, industrial, or household setting