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Chloroxine
go.drugbank.com/drugs/DB01243ApprovedWithdrawnChloroxine is a compound used in some shampoos for the treatment of dandruff and seborrheic dermatitis of the scalp.
Palopegteriparatide
go.drugbank.com/drugs/DB18676ApprovedInvestigational[L51134] Palopegteriparatide was first approved by the EMA on November 17, 2023, for the treatment of hyperparathyroidism.[L51134] On August 8, 2024, palopegteriparatide was also approved by the FDA. … [L51134] PTH(1-34) contains the N-terminal part of the endogenous PTH molecule.
Synonyms: )-peptide of parathyroid hormone (Homo sapiens parath, Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34Thonzonium
go.drugbank.com/drugs/DB09552ApprovedIt is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. … A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.
Hyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigationalA purified preparation of the enzyme recombinant human hyaluronidase. … [L13338] The action of hyaluronidase was first described in 1936, and named in 1939.
Tideglusib
go.drugbank.com/drugs/DB12129ApprovedInvestigationalWithdrawn[A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012. … Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy.
Sulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawn[A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. … [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in individual European countries.[L24679]
Synonyms: N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamideProducts: SULPIVERT 50 MG, SULPIDIN TABLET 200 mgRanolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigational[A189234] Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. … [L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.[L5440]
Products: RANOLAZINA EG, Rande 375 mg RetardtablettenAltanserin
go.drugbank.com/drugs/DB19972InvestigationalAltanserin has a monoisotopic molecular weight of 411.14 Da. … The usage of the INN stem '-anserin' in the name indicates that Altanserin is a serotonin receptor antagonist.
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingPentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: 4-O-METHYL-.ALPHA.-D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULFATE, 4-O-METHYL-.ALPHA.-D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULPHATEProducts: ELMIRON 100 MG KAPSÜL, 100 ADET, Elmidam 100 mg Sert Kapsül, 100 ADETHyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigationalHyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. … [A228423] Research into the action of hyoscyamine in published literature dates back to 1826.