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Displaying results 2681 - 2690 of 5451 in total
  1. Drug

    DCFBC F-18

    go.drugbank.com/drugs/DB14772
    Investigational

    DCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).

  2. Drug

    Lobeglitazone

    go.drugbank.com/drugs/DB09198
    Investigational

    Unlike [DB01132], which is a dual PPAR agonist at PPAR-alpha and PPAR-gamma, Lobeglitazone is a pure PPAR-alpha agonist. … It primarily functions as an insulin sensitizer by binding and activating Peroxisome Proliferator-Activated Receptors (PPAR) gamma within fat cells.

  3. Drug

    Dibromothymoquinone

    go.drugbank.com/drugs/DB04646
    Experimental

    At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem] … At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist.

  4. Drug

    KB001

    go.drugbank.com/drugs/DB05222
    Investigational

    KB001 is a Humaneered™ PEGylated monoclonal antibody fragment for the treatment of life-threatening Pseudomonas aeruginosa infections, a common problem of cystic fibrosis and mechanically ventilated patients.

  5. Drug

    Erdosteine

    go.drugbank.com/drugs/DB05057
    ApprovedInvestigational

    It is a _thiol_ derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis. … It also combats the effects of free radicals resulting from cigarette smoke. Erdosteine has been shown to be safe and well tolerated in clinical trials.

    Products: ERDOS CAPSULE 300 MG, ERDOSTIN 225 MG SAŞE, 20 ADET
  6. Drug

    Fluocortolone pivalate

    go.drugbank.com/drugs/DB15777
    Investigational

    Mixtures: Doloproct 1 mg + 40 mg Zäpfchen
  7. Drug

    Glutethimide

    go.drugbank.com/drugs/DB01437
    ApprovedIllicit

    Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.

  8. Drug

    Perospirone

    go.drugbank.com/drugs/DB08922
    Investigational

    It is commonly present as the hydrated hydrochloride salt form. … It also displays affinity towards 5HT1A receptors as a partial agonist.

  9. Drug

    JSM 6427

    go.drugbank.com/drugs/DB06139
    Investigational

    It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age of 55.

  10. Drug

    Depemokimab

    go.drugbank.com/drugs/DB18846
    ApprovedInvestigational

    Depemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug. Its long duration of action is granted by seven amino acid substitutions in the heavy chain sequence. Depemokimab blocks interleukin-5 (IL-5)...