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Radium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalIt was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which was formerly called Alpharadin. … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases.
Sulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigational[L51768] Sulopenem etzadroxil was approved by the FDA in October 2024 for the treatment of uncomplicated urinary tract infections. … Like other beta-lactam antibacterials, it is a time-dependent inhibitor of bacterial cell wall synthesis.
Insulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L50763] It has also been approved in Japan and Australia. … It is a re-engineered version of the ultra long-acting oral basal insulin OI338, with several modifications introduced to significantly extend the half-life.
Difamilast
go.drugbank.com/drugs/DB14987ApprovedInvestigationalIt is approved in Japan and the United States.[L55042, A275424, L56052] … [L56052, A275420] This skin disease occurs most frequently in children and can have an onset as early as within the first 2 years of life.
Insulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigational[A18561,A18562,A18563,A18564,A174934] Marketed as the brand name product Tresiba, insulin degludec has a duration of action up to 42 hours allowing for once-daily dosing, typically at bedtime. … [A18561,A18562,A18563,A18564,A174934] Compared to endogenous insulin, insulin degludec has an added hexadecanedioic acid on lysine at the B29 position, allowing for the formation of multi-hexamers.
Ethoheptazine
go.drugbank.com/drugs/DB08988ApprovedWithdrawnIt is a phenazepine based opioid analgesic. It was invented in the 1950s and is related to other drugs such as proheptazine. Ethoheptazine is no longer marketed in the United States.
Succimer
go.drugbank.com/drugs/DB00566ApprovedInvestigationalA mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Meticillin
go.drugbank.com/drugs/DB01603ApprovedInvestigationalIt is inactivated by gastric acid so administered by injection.
Phosphocreatine
go.drugbank.com/drugs/DB13191InvestigationalNutraceuticalIt is primarily found endogenously in the skeletal muscles of vertebrates where it serves a critical role as a rapidly acting energy buffer for muscle cell actions like contractions via its ability to