Succimer is a mercaptodicarboxylic acid heavy metal chelator used in the treatment of heavy metal poisoning. A medication used to treat poisoning with some types of metal.
- Mechanism
- Curator reviewed
Succimer is a heavy metal chelator. It binds with high specificity to ions of lead in the blood to form a water-soluble complex that is subsequently excreted by the kidneys. Succimer can also chelate mercury, cadmium, and arsenic in this manner.
- Primary indication
- For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 µg/dL.Curator reviewed · 4 structured indications
- Formula / weight
- C4H6O4S2 · 182.21 g/mol (avg)
- First approval
- United States, 1991
- Also known as
- DIM-SA · DMS-A · DMSA · meso-dimercaptosuccinic acid
- Code names
- RO 1-7977
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
ACTRVOBWPAIOHC-XIXRPRMCSA-NSMILESOC(=O)[C@@H](S)[C@@H](S)C(O)=OWhat you can answer from here — as of September 13, 2026
4Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which other approved drugs treat the same conditions as Succimer, and which companies have late-stage candidates in those indications?
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