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N,N,N-trimethylglycinium
go.drugbank.com/drugs/DB04455InvestigationalAs a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. … A naturally occurring compound that has been of interest for its role in osmoregulation.
Synonyms: N,N,N-trimethylglyciniumSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[L39267] Sirolimus was also investigated in other cancers such as skin cancer, Kaposi’s Sarcoma, cutaneous T-cell lymphomas, and tuberous sclerosis. … Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: RENACEPT, LIKMUN-EPhenyltoloxamine
go.drugbank.com/drugs/DB11160ApprovedIt is a H1 receptor blocker and a member of the ethanolamine class of antihistaminergic drugs. … Nevertheless, phenyltoloxamine is used to a fairly limited extent in contemporary medicine, with only very few products involving it as an active ingredient.
Caffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigationalThis correlates to about 1 in 10 births. … Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.
Synonyms: 1-methyltheobromine, 7-methyltheophyllineMixtures: Green Guard Pain and Ache Relief, Green Guard Extra Strength Pain ReliefClonixin
go.drugbank.com/drugs/DB09218InvestigationalClonixin is a non-steroidal anti-inflammatory drug.
Mixtures: DOBRIX ®, MIGRADORIXINA® COMPRIMIDOSCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingNGX267
go.drugbank.com/drugs/DB05152InvestigationalNGX267 is a muscarinic agonist. It is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
Categories: Heterocyclic Compounds, 1-RingMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAlthough demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation
Synonyms: 3-carboxy-4-hydroxyaniline, 5-ASAProducts: PENTASA® ENEMA 1 G, PENTASA 1 G ENEMA,7 ADETOdevixibat
go.drugbank.com/drugs/DB16261ApprovedInvestigational[L34803] Previous therapies for PFIC included a bile acid sequestrant such as [ursodeoxycholic acid]. … Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 2-Ring