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Displaying results 2681 - 2690 of 10000 in total
  1. Drug

    Tomligisiran

    go.drugbank.com/drugs/DB19330
    Investigational

    B (CHB)). … Tomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis

    Synonyms: RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN, -9-YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACETYLAMI
  2. Drug

    Itopride

    go.drugbank.com/drugs/DB04924
    Investigational

    Itopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.

    Synonyms: N-(p-(2-(Dimethylamino)ethoxy)benzyl)veratramideProducts: DOIZ 50 MG FC TABLET, Itomed 50 mg Filmtabletten
  3. Drug

    BF-844

    go.drugbank.com/drugs/DB17801
    Investigational

    Synonyms: 1-(4-chloro-3,5-diphenyl-pyrazolo(3,4-c)pyridazin-1-yl)-2-methyl-propan-2-ol, 1-(4-chloro-3,5-diphenyl-pyrazolo[3,4-C]pyridazin-1-yl)-2-methyl-propan-2-ol
  4. Drug

    DPA-714 F-18

    go.drugbank.com/drugs/DB19189
    Investigational

    Synonyms: N,n-diethyl-(2-(4-(2-(18f)fluoroethoxy)phenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidine-3-yl)acetamide, Pyrazolo(1,5-a)pyrimidine-3-acetamide, n,n-diethyl-2-(4-(2-(fluoro-18f)ethoxy)phenyl)-5,7-dimethyl-
  5. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell. … Sipavibart is a recombinant human IgG1 monoclonal antibody that is long-acting.

    Synonyms: Immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody, Immunoglobulin G1 [242-phenylalanine,243-glutamic acid,260-tyrosine,262-threonine,264-glutamic acid,339-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding
  6. Drug

    Deucrictibant

    go.drugbank.com/drugs/DB18303
    Investigational

    Synonyms: Acetamide, N-[(1S)-1-[3-chloro-5-fluoro-2-[[[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5- yl)-8-quinolinyl]oxy]methyl]phenyl]ethyl-1-d]-2-(difluoromethoxy)-, N-[(1S)-1-[3-chloro-5-fluoro-2-({[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5-yl)quinolin-8-yl]oxy}methyl)phenyl](1-2H)ethyl]-2-(difluoromethoxy)acetamide
  7. Drug

    Selonsertib

    go.drugbank.com/drugs/DB14916
    Investigational

    Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).

    Synonyms: 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide, 5-(4-Cyclopropyl-1H-imidazol-l-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamideCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    AZD2315

    go.drugbank.com/drugs/DB06540
    Experimental

    The drug AZD2315, an immunosuppressant developed by AstraZeneca, was in Phase 1 clinical trials for the treatment of rheumatoid arthritis but was discontinued during this phase

    Synonyms: L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, ACETATE (1:2), L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, DIACETATE
  9. Drug

    Zilucoplan

    go.drugbank.com/drugs/DB15636
    ApprovedInvestigational

    Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses.

    Synonyms: -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3, .-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA.-HYDROXY-, 15-ETHER WITH N-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA.Products: Zılbrysq 23 mg/0,574 mL SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (7 Adet), Zılbrysq 16,6 mg/0,416 mL SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (7 Adet)
  10. Drug

    Clenbuterol

    go.drugbank.com/drugs/DB01407
    ApprovedInvestigationalVet approved

    A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.

    Synonyms: 1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol, 4-amino-α-((tert-butylamino)methyl)-3,5-dichlorobenzyl alcoholMixtures: AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 ML, SERBOL-G