Deucrictibant

DB18303InvestigationalSmall molecule

Deucrictibant: Overview.

Mechanism: Pharmacologically active on B2 bradykinin receptor
Curator reviewed
Formula / weight: C₂₅H₂₃ClF₃N₅O₃ · 534.94 g/mol (avg)
Also known as: Acetamide, N-[(1S)-1-[3-chloro-5-fluoro-2-[[[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5- yl)-8-quinolinyl]oxy]methyl]phenyl]ethyl-1-d]-2-(difluoromethoxy)- · N-[(1S)-1-[3-chloro-5-fluoro-2-({[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5-yl)quinolin-8-yl]oxy}methyl)phenyl](1-2H)ethyl]-2-(difluoromethoxy)acetamide · N-{(1S)-1-[3-chloro-5-fluoro-2-({[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5-yl)quinolin-8- yl]oxy}methyl)phenyl](1-2H)ethyl}-2-(difluoromethoxy)acetamide
Code names: PHA-022121 · PHA-121 · PHVS416 · PHVS-719

Resolves to

Compound

Structure

InChIKeyZTCLCSCHTACERP-WTDRUJNCSA-NSMILES[2H][C@@](C)(NC(=O)COC(F)F)C1=CC(F)=CC(Cl)=C1COC1=CC=CC2=C(C=C(C)N=C12)C1=NC=NN1C

Targets

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Deucrictibant, and which of those have an active Phase 3 trial?

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