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Vigabatrin
go.drugbank.com/drugs/DB01080ApprovedInvestigational[A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual … [L13616] It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA.
Products: SABRIL 500 MG 50 SASE, Vigabatrin for Oral SolutionVitamin E
go.drugbank.com/drugs/DB00163ApprovedInvestigationalNutraceuticalVet approvedThough this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA[FDA Label]. … In 1922, vitamin E was demonstrated to be an essential nutrient[A32448].
Mixtures: Omega-3 Rx Complete, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHACategories: Compounds used in a research, industrial, or household settingClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approvedClindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. … [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been used off-label in the treatment of toxoplasmosis, malaria, and babesiosis.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: CLINDAMICINA SAME, Nu-clindamycinThiotepa
go.drugbank.com/drugs/DB04572ApprovedInvestigationalN,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. … It is also used as conditioning for Bone marrow transplantation. Its main toxicity is myelosuppression.
Synonyms: N,N′,N′′-tri-1,2-ethanediyl-, Phosphorothioic triamide, N,N′,N′′-tri-1,2-ethanediyl-Products: Thio Tepa Inj 15mg/vial, TEPADINA 15 mg powder for concentrate for solution for infusionCefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigational[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical … Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Maxipime for Injection -pws IV Im 1g, Maxipime for Injection-pws IV 2gmRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigationalIt is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery … or mechanical ventilation.
Products: ROCURONIO BROMURO SALF, ROCUREX(R)100MGBudesonide
go.drugbank.com/drugs/DB01222ApprovedInvestigational[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619] … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.
Mixtures: SYMBICORT RAPIHALER SUSPENSION FOR INHALATION 80/4.5 mcg/actuation, SYMBICORT RAPIHALER SUSPENSION FOR INHALATION 160/4.5 mcg/actuationCategories: Corticosteroids for Systemic Use, Corticosteroids for inhalation useMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.
Categories: Drugs for Functional Gastrointestinal Disorders, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnIt is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences. … A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes.
Categories: Interferon Type IProducts: ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 ml, ROFERON - A ROCHE SOLUCION INYECTABLE 3 K/U.I.Furosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approvedIn addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients … [L7958] Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure.
Mixtures: Rx-Specimen Collection KitCategories: Antihypertensive Agents Indicated for Hypertension, Non Potassium Sparing Diuretics