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Abrocitinib
go.drugbank.com/drugs/DB14973ApprovedInvestigationalAbrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). … JAK inhibitors recently attracted more attention as potential treatments for inflammatory disorders, as JAK inhibition is associated with rapid and sustained anti-inflammatory efects.
Iptacopan
go.drugbank.com/drugs/DB16200ApprovedInvestigationalIptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor … [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase.
Categories: Compounds used in a research, industrial, or household settingAtrasentan
go.drugbank.com/drugs/DB06199ApprovedInvestigationalAtrasentan is a novel, selective endothelin A receptor antagonist (SERA). … [L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist
Categories: Endothelin A Receptor AntagonistsEtonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.
Colfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawnColfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome.
Glutaral
go.drugbank.com/drugs/DB03266InvestigationalOne of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
Categories: Compounds used in a research, industrial, or household settingEHC18
go.drugbank.com/drugs/DB05114ExperimentalEHC18 is an immune regulation medicine. It is a broad spectrum of specific HCV proteins.
D-glyceraldehyde 3-phosphate
go.drugbank.com/drugs/DB02263ExperimentalAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Pyruvic acid
go.drugbank.com/drugs/DB00119ApprovedInvestigationalNutraceuticalAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures.
Synonyms: a-Ketopropionic acid