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Dezamizumab
go.drugbank.com/drugs/DB15153InvestigationalDezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS APCS (AMYLOID P COMPONENT SERUM, SERUM AMYLOID P COMPONENT, SAP, PENTRAXIN-2, PTX2)), HUMANIZED MONOCLONAL ANTIBODY, recombinant monoclonal antibody to human serum amyloid P componentHydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedMixtures: Actinac Pwr, Alcortin ACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersArachidonic Acid Metabolism
smpdb.ca/view/SMP0000075MetabolicThis pathway describes the production and subsequent metabolism of arachidonic acid, an omega-6 fatty acid. In resting cells arachidonic acid is present in the phospholipids (especially phosphatidylethanolamine and phosphatidylcholine) o...
Enzymes: Prostaglandin E synthaseAcetylsalicylic Acid Action Pathway
smpdb.ca/view/SMP0000083Drug actionAcetylsalicylic acid, also known as ASA or aspirin, belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). In addition to its anti-inflammatory properties, aspirin also acts as an analgesic, antipyretic and ...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Acetylsalicylic acid · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseKetoprofen Action Pathway
smpdb.ca/view/SMP0000085Drug actionKetoprofen (also known as (RS)-2-(3-benzoylphenyl)-propionic acid) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.. Ketoprofen ...
Enzymes: Prostaglandin E synthaseMeloxicam Action Pathway
smpdb.ca/view/SMP0000106Drug actionMeloxicam is a non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic properties. Most NSAIDs, such as ibuprofen and naproxen, are non-selective prostaglandin G/H synthase (a.k.a. cyclooxygenase or COX) inhibitors th...
Enzymes: Prostaglandin E synthaseDiflunisal Action Pathway
smpdb.ca/view/SMP0000289Drug actionDiflunisal (also known as Dolobid) is a prostaglandin G/H synthase inhibitor that can inhibit prostaglandin G/H synthase 1 and 2 which prevent the production of prostaglandin. Therefore, diflunisal can be used for treating prostaglandin-...
Enzymes: Prostaglandin E synthaseFlurbiprofen Action Pathway
smpdb.ca/view/SMP0000697Drug actionFlurbiprofen (also named Ansaid or Froben) is a nonsteroidal anti-inflammatory drugs. It is used for treatment of moderate pain. Flurbiprofen can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 a...
Drugs: Glutamic acid · Glutathione · Flurbiprofen · Dinoprostone · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseMagnesium Salicylate Action Pathway
smpdb.ca/view/SMP0000698Drug actionMagnesium Salicylate is a nonsteroidal anti-inflammatory drug. It can be used to treat mild to moderate muscular pain such as headaches, general back pain and other joint pain. Magnesium Salicylate can block prostaglandin synthesis by th...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Magnesium salicylate +5 moreEnzymes: Prostaglandin E synthaseLornoxicam Action Pathway
smpdb.ca/view/SMP0000700Drug actionLornoxicam (also named Chlortenoxicam or Xefocam) is a nonsteroidal anti-inflammatory drug. It can be used to treat moderate pain such as pain relieving. It can also treat swelling and fever reducing. Lornoxicam can block prostaglandin s...
Enzymes: Prostaglandin E synthase