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Venanprubart
go.drugbank.com/drugs/DB18891InvestigationalVenanprubart is under investigation in clinical trial NCT05781451 (Anti-btla Agonist Therapy in Subjects With Primary Sjogren's Syndrome).
JNJ-39758979
go.drugbank.com/drugs/DB18899InvestigationalJNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-PYRIMIDINAMINE, 4-((3R)-3-AMINO-1-PYRROLIDINYL)-6-(1-METHYLETHYL)-INCB-086550
go.drugbank.com/drugs/DB18901InvestigationalINCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).
Synonyms: 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN-8-YL)AMINO)-2,2'-DIMETHYL(1,1'-BIPHENYL)-3-YL)-5-BENZOXAZOLYL)METHYL)-, (3R)-BMS-770767
go.drugbank.com/drugs/DB18902InvestigationalBMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-(8-(2-CHLOROPHENOXY)(1,2,4)TRIAZOLO(4,3-A)PYRIDIN-3-YL)BICYCLO(2.2.1)HEPTAN-1-OL, BICYCLO(2.2.1)HEPTAN-1-OL, 4-(8-(2-CHLOROPHENOXY)-1,2,4-TRIAZOLO(4,3-A)PYRIDIN-3-YL)-ANC-501
go.drugbank.com/drugs/DB18907InvestigationalANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4-triazole-4-acetamideApelin
go.drugbank.com/drugs/DB18909InvestigationalApelin is under investigation in clinical trial NCT03449251 (A Series of Pilot Studies to Evaluate the Haemodynamic and Metabolic Effects of Apelin and Relaxin).
Cardiopet
go.drugbank.com/drugs/DB18913InvestigationalCardiopet is under investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects).
Synonyms: 2-((1s,2r)-2-(5-(fluoro-18f)tridecyl)cyclopropyl)acetic acid, Trans-9(rs)-18f-fluoro-3,4(rs,rs)-methyleneheptadecanoic acidTeropavimab
go.drugbank.com/drugs/DB18916InvestigationalTeropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection
Synonyms: Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappaEdecesertib
go.drugbank.com/drugs/DB18917InvestigationalEdecesertib is under investigation in clinical trial NCT05629208 (Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)).
Synonyms: 3-Pyridinecarboxamide, 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-, 4-{[(1R)-1-cyanoethyl]amino}-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3- methylbutyl]pyridine-3-carboxamideGefurulimab
go.drugbank.com/drugs/DB18928InvestigationalGefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).