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Suramin
go.drugbank.com/drugs/DB04786InvestigationalIt is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. … (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin is manufactured by Bayer in Germany as Germanin®.
Foscarnet
go.drugbank.com/drugs/DB00529ApprovedInvestigationalAn antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Products: FOSCAVIR INFUSION 24 mg/ml, Foscarnet Tillomed 24 mg/ml InfusionslösungDiroximel fumarate
go.drugbank.com/drugs/DB14783ApprovedInvestigational[A176474] It is the main cause of neurological disability not caused by trauma in the young adult population of both North America and Europe.
Sulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigationalLike other beta-lactam antibacterials, it is a time-dependent inhibitor of bacterial cell wall synthesis. … [L51858] It is administered in combination with [probenecid] in order to increase antibiotic exposure.[L51768]
Chymopapain
go.drugbank.com/drugs/DB06752ApprovedWithdrawnIt is currently discontinued.[L2487] … [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity.[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982.
Huperzine A
go.drugbank.com/drugs/DB04864ApprovedInvestigationalWithdrawnRecently in clinical trials in China, it has demonstrated neuroprotective effects. … It is currently being investigated as a possible treatment for diseases characterized by neurodegeneration – particularly Alzheimer’s disease.
Acetohydroxamic acid
go.drugbank.com/drugs/DB00551ApprovedInvestigationalIt is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections. … In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Products: CIFLOXIN 200 MG., QUINOPRON ® INYECTABLE 200 MGHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedIt can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.