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Displaying results 2721 - 2730 of 10000 in total
  1. Drug

    Coenzyme M

    go.drugbank.com/drugs/DB09110
    ApprovedInvestigational

    Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]

    Synonyms: Coenzym M, Coenzima MMixtures: IFEX and MESNEX, IFEX and MESNEX
  2. Drug

    Zonisamide

    go.drugbank.com/drugs/DB00909
    ApprovedInvestigational

    The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … [L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors

    Synonyms: Benzo[d]isoxazol-3-yl-methanesulfonamide, 1,2-Benzisoxazole-3-methanesulfonamideCategories: Heterocyclic Compounds, 1-Ring, Calcium-Regulating Hormones and Agents
  3. Drug

    Estramustine

    go.drugbank.com/drugs/DB01196
    ApprovedWithdrawn

    A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

    Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 SubstratesSynonyms: Estradiol 3-(N,N-bis(2-chloroethyl)carbamate), 17β-Estradiol 3-(bis(2-chloroethyl)carbamate)
  4. Drug

    Methylergometrine

    go.drugbank.com/drugs/DB00353
    ApprovedInvestigational

    A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)

    Synonyms: D-lysergic acid 1-butanolamide, 9,10-Didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamideInternational brands: Ingagen-M, Partan M
  5. Drug

    Saw palmetto

    go.drugbank.com/drugs/DB14360
    Approved

    Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Saw Palmetto Fruit (Serenoa Repens (W. Bartram) Small (Sabal Serrulata (Michaux) Nichols)), Sabalis Serrulatae Fructus (Serenoa Repens (W. Bartram) Small (Sabal Serrulata (Michaux) Nichols))Mixtures: PROSTAGOOD PLUS KAPSÜL, 120 ADET, PROSTAGOOD PLUS KAPSÜL, 60 ADET
  6. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996.

    Synonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate, 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamateMixtures: Phentermine and topiramate, Phentermine and topiramate
  7. Drug

    Etoposide toniribate

    go.drugbank.com/drugs/DB17255
    Investigational

    Synonyms: ((4rs)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl4-((5r,5ar,8ar,9s)-9-((4,6-o-((1r)-ethane-1,1-diyl)-.beta., Carbonic acid, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-((5r,5ar,8ar,9s)-9-((4,6-o-(1r)-ethylidene-.beta.
  8. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. … [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion.

    Synonyms: (S)-omeprazole, (S)-(−)-omeprazoleMixtures: OCAM PROTECT 15 MG, OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADA
  9. Drug

    Trihexyphenidyl

    go.drugbank.com/drugs/DB00376
    ApprovedInvestigational

    [L31843] Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768] … Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.

    Categories: Heterocyclic Compounds, 1-RingProducts: ACA (5 mg.), BENZHEXOL TABLETS 5 MG
  10. Drug

    Iobitridol

    go.drugbank.com/drugs/DB12407
    ApprovedWithdrawn

    Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

    Categories: X-Ray Contrast Media, Iodinated, Compounds used in a research, industrial, or household settingProducts: XENETİX 300 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, Xenetix 250 (250 mg Jod/ml) - Parenterale Röntgenkontrastmittellösung