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Cilazapril
go.drugbank.com/drugs/DB01340ApprovedInvestigationalIt belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these varieties are available in the United States.
Mixtures: ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADET, INHIBACE PLUS 5 MG TABLET, 28 ADETCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalIt is a _non-ergot dopamine agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) [A176867]. … It was first approved by the FDA in 1997 [L5882].
Synonyms: (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamineInternational brands: Sifrol ERFludarabine
go.drugbank.com/drugs/DB01073ApprovedInvestigationalFludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Categories: Heterocyclic Compounds, 2-Ring, DNA (Cytosine-5-)-Methyltransferases, antagonists & inhibitorsSynonyms: 2-F-ARAA, 2-fluoro ARA-ARopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIn 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPINIROL-NEURAX 5 MG, ROPINIROL AL 5 MG FILMTABLAllopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalIt was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942].
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidineZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedZinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. … It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Mixtures: AVi VITAMIN C 1000 mg with Zinc, Real Ginger, Honey, Lemon and Lemongrass, FERROZINC - G SURUP, 100 MLProducts: Zinc (gluconate) 10 Mg Tablets, ZINC 50 MG.Veru-111
go.drugbank.com/drugs/DB16462InvestigationalThese trials aimed to evaluate its efficacy, safety, and tolerability in conditions such as SARS-CoV-2 infection, metastatic castration-resistant prostate cancer (mCRPC), respiratory distress syndrome
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-, [2-(1H-indol-3-yl)-1H-imidazol-4-yl](3,4,5-trimethoxyphenyl)methanoneLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigational[A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
Mixtures: Dg Health Anti Diarrheal Anti GasCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin … [DB00146] undergoes hydroxylation to form calcitriol via 1α-hydroxylase (CYP27B1) activity [A26353]. Calcitriol is considered to be the most potent metabolite of vitamin D in humans [A3366].
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1α,25(OH)2D3, 1-alpha-25-Dihydroxyvitamin D3Metandienone
go.drugbank.com/drugs/DB13586ApprovedWithdrawnAlthough it is prohibited in and outside competition by the World Anti-Doping Agency, metandienone continues to be marketed and misused as a performance-enhancing drug in sports. … It was introduced to the market in the 1960s but later discontinued and withdrawn from the market.
Products: SIROBOLIN ŞURUP, 120 ML, ไดอาบอล - 5