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Displaying results 2741 - 2750 of 10000 in total
  1. Drug

    Londamocitinib

    go.drugbank.com/drugs/DB19190
    Investigational

    Londamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high

    Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-
  2. Drug

    Dovramilast

    go.drugbank.com/drugs/DB16242
    Investigational

    Dovramilast is under investigation in clinical trial NCT01300208 (To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cut...

    Synonyms: Cyclopropanecarboxamide, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-3-oxo-1H-isoindol-4-yl]-, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2- (methanesulfonyl)ethyl]-3-oxo-2,3-dihydro-1H-isoindol- 4-yl}cyclopropanecarboxamideCategories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 Inhibitors
  3. Drug

    NS-398

    go.drugbank.com/drugs/DB14060
    Experimental

    NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.

    Synonyms: N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide
  4. Drug

    Deanol

    go.drugbank.com/drugs/DB13352
    Investigational

    Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups.

    Synonyms: 2-(dimethylamino)ethanol
  5. Drug

    Abdavomeran

    go.drugbank.com/drugs/DB15695
    Investigational

    [L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived … [L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding immunoglobulin levels and 50% serum neutralizing titers higher than those observed in [COVID

    Synonyms: BNT162b1 SARS-CoV-2 Vaccine
  6. Drug

    Dutasteride

    go.drugbank.com/drugs/DB01126
    ApprovedInvestigational

    [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland. … It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner.

    Mixtures: DUODART 0,5 MG/0,4 MG KAPSÜL,7 KAPSÜL, Duodart 0,5 mg/0,4 mg HartkapselnCategories: 5-alpha Reductase Inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Butanixin

    go.drugbank.com/drugs/DB20696
    Experimental

    Butanixin is a small molecule drug. Butanixin has a monoisotopic molecular weight of 270.14 Da.

    Synonyms: 2-(p-butanilino)nicotinic acid
  8. Drug

    AVR-48

    go.drugbank.com/drugs/DB18294
    Investigational

    Synonyms: -d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy-, 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside
  9. Drug

    Human interleukin-6

    go.drugbank.com/drugs/DB15060
    Investigational

    Human interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).

    Synonyms: HUMAN B-CELL STIMULATORY FACTOR 2, HUMAN INTERFERON BETA-2
  10. Drug

    EHP-102

    go.drugbank.com/drugs/DB16933
    Experimental

    Synonyms: 2-(3,7-Dimethyl-Octa-2, 6-Dienyl)-6-Ethylamino-3-Hydroxy-5-Pentyl-[1,4]Benzoquinone, 2-(3,7-Dimethyl-octa-2, 6-dienyl)¿6-ethylamino-3-hydroxy-5-pentyl-[1,4]benzoquinone