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Esaxerenone
go.drugbank.com/drugs/DB15207InvestigationalEsaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension
Categories: Heterocyclic Compounds, 1-RingMK-0736
go.drugbank.com/drugs/DB15209InvestigationalMK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).
Chlorotoxin
go.drugbank.com/drugs/DB15210InvestigationalChlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
BMS-986104
go.drugbank.com/drugs/DB15214InvestigationalBMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
KRN-5500
go.drugbank.com/drugs/DB15215InvestigationalKRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
Categories: Heterocyclic Compounds, 2-RingSynonyms: 6-[4-Deoxy-4-[(2E,4E)-tetradecadienoylglycyl]amino-L-glycero-B-L-manno-heptopyranosyl]amino-9H-purineGastric inhibitory polypeptide
go.drugbank.com/drugs/DB15217InvestigationalGastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without
Pozelimab
go.drugbank.com/drugs/DB15218ApprovedInvestigational[A261120] Pozelimab is a human, monoclonal immunoglobulin G4<sup>P</sup> antibody against the terminal complement protein C5. … CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US.
Tomivosertib
go.drugbank.com/drugs/DB15219InvestigationalTomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'-dioneSeliforant
go.drugbank.com/drugs/DB15220InvestigationalSeliforant is under investigation in clinical trial NCT01260753 (Proof of Activity Study of UR-63325 in Allergic Rhinitis Induced by Nasal Challenge).
Categories: Heterocyclic Compounds, 1-RingMitazalimab
go.drugbank.com/drugs/DB15225InvestigationalMitazalimab is under investigation in clinical trial NCT02379741 (ADC-1013 First-in-Human Study).