This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Chlorotoxin
DrugBank Accession Number
DB15210
Background

Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).

Type
Biotech
Groups
Investigational
Synonyms
Not Available

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
06UV5RFW57
CAS number
163515-35-3

References

General References
Not Available
Wikipedia
Chlorotoxin

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Unknown StatusTreatmentAnaplastic Astrocytoma (AA) / GBM / Glioblastoma Multiforme (GBM) / Gliomas, Malignant / Gliosarcoma / Oligoastrocytoma1
1CompletedTreatmentAdenocarcinoma, Prostate / Breast Cancer / Colorectal Carcinoma (CRC) / Gliomas / Malignant Melanoma of Skin / Malignant Neoplasm of Pancreas / Non-Small Cell Lung Carcinoma (NSCLC) / Primary Solid Tumors1
1RecruitingTreatmentRecurrent Glioblastoma / Recurrent Malignant Gliomas / Recurrent WHO Grade II Glioma / Recurrent WHO Grade III Glioma1
1Unknown StatusTreatmentAstrocytomas / GBM / Glioblastoma Multiforme (GBM) / Gliomas, Malignant / Oligodendrogliomas1
1, 2TerminatedTreatmentMalignant Melanoma of Skin / Melanoma, Malignant / Metastatic Melanoma1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at May 20, 2019 15:00 / Updated at June 12, 2020 16:53