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Glycyrrhiza glabra
go.drugbank.com/drugs/DB14312ApprovedInvestigationalWithdrawnGlycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Toe Corrector Composite, Medi SM 24K Gold Hydrogel Peptide Mask PackSynonyms: Glycyrrhiza Glabra L Rhizome Extract, Ae-licoriceLomitapide
go.drugbank.com/drugs/DB08827Approved[A7367] Lomitapide was first approved by the FDA in December 2012 and the EMA in July 2013 as an adjunct to a low-fat diet and other lipid-lowering treatments.[A275444, A275446] … apo B-containing lipoproteins in the liver and intestines.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A InhibitorsSynonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDEIdarucizumab
go.drugbank.com/drugs/DB09264ApprovedAs a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease … Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its
Products: PRAXBIND®, PRAXBİND 50 MG/ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADETTrichlormethiazide
go.drugbank.com/drugs/DB01021ApprovedVet approvedA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Categories: Heterocyclic Compounds, 2-RingCod liver oil
go.drugbank.com/drugs/DB11321ApprovedNutraceuticalVet approvedAlso being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. … It is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis while meeting the consumption criteria.
Products: ChildLife™ Essentials Cod Liver Oil (Strawberry Flavour)Ranolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigational[L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.[L5440] … [A189234] Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: RANEXICOR ® 500, RANEXICOR ® 1000Tetradecyl hydrogen sulfate (ester)
go.drugbank.com/drugs/DB11328ApprovedSodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report of injecting a 1% solution into spider angiomas in 144 patients was made. … Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids
Synonyms: 7-Ethyl-2-methyl-4-undecanol sulfateInternational brands: Fibro-Vein 3%Teprotumumab
go.drugbank.com/drugs/DB06343ApprovedInvestigationalTeprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. … multiple invasive surgeries - teprotumumab is the first drug ever approved for the treatment of TED and therefore represents a significant step forward in the treatment this disease.
Categories: Insulin-like Growth Factor-1 Receptor InhibitorSynonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimerCefiderocol
go.drugbank.com/drugs/DB14879ApprovedInvestigational[A189057] It represents a significant addition to antibacterial treatment option as it has proven to be effective *in vitro* against multidrug resistant strains including extended spectrum β-lactamase … Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingVelpatasvir
go.drugbank.com/drugs/DB11613ApprovedInvestigationala high barrier to resistance [L852]. … Epclusa is the first combination HCV product indicated for the treatment of all genotypes of Hepatitis C with or without cirrhosis.
Mixtures: EPCLUSA®Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors